Thursday, October 27, 2016

Ascorbic Acid Quick Melts


Generic Name: ascorbic acid (vitamin C) (as KORE bik AS id)

Brand Names: Acerola, Ascorbic Acid Quick Melts, C-Time, C/Rose Hips, Cecon, Cemill 1000, Cemill 500, Ester-C, N Ice with Vitamin C, Sunkist Vitamin C, Vicks Vitamin C Drops, Vitamin C, Vitamin C TR, Vitamin C with Rose Hips


What is ascorbic acid?

Ascorbic acid (vitamin C) occurs naturally in foods such as citrus fruit, tomatoes, potatoes, and leafy vegetables. Ascorbic acid is important for bones and connective tissues, muscles, and blood vessels. Vitamin C also helps the body absorb iron, which is needed for red blood cell production.


Ascorbic acid is used to treat and prevent vitamin C deficiency.


Ascorbic acid may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about ascorbic acid?


You should not use this medication if you have ever had an allergic reaction to ascorbic acid.

Ask a doctor or pharmacist about using ascorbic acid if you have kidney disease or a history of kidney stones, liver disease (especially cirrhosis), or an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD).


It is not known whether ascorbic acid is harmful to an unborn baby or a nursing baby. Some vitamins and minerals are needed during pregnancy or for breast milk production, but some may be harmful if taken in large doses. Do not take ascorbic acid without telling your doctor if you are pregnant or breast-feeding.

Ascorbic acid can be harmful to the kidneys, and this effect is increased when ascorbic acid is used together with other medicines that can harm the kidneys. Before taking ascorbic acid, tell your doctor if you are receiving chemotherapy, or using medicines to treat a bowel disorder, medication to prevent organ transplant rejection, antiviral medications, pain or arthritis medicines, or any injected antibiotics. You may need dose adjustments or special tests when taking any of these medications together with ascorbic acid.


Before taking ascorbic acid, tell your doctor about all other medications you take.


Stop using ascorbic acid and call your doctor at once if you have severe pain in your lower back or side, blood in your urine, pain when you urinate, severe or ongoing diarrhea, or feel like you might pass out.

What should I discuss with my healthcare provider before taking ascorbic acid?


You should not use this medication if you have ever had an allergic reaction to ascorbic acid.

Ask a doctor or pharmacist about using ascorbic acid if you have:


  • kidney disease or a history of kidney stones;

  • liver disease (especially cirrhosis); or


  • an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD).




It is not known whether ascorbic acid is harmful to an unborn baby. Some vitamins and minerals can harm an unborn baby if taken in large doses. You may need to use a prenatal vitamin specially formulated for pregnant women. Do not take ascorbic acid without telling your doctor if you are pregnant. Ascorbic acid can pass into breast milk, but it is not known whether it would be harmful to a nursing baby. Some vitamins and minerals are needed for breast milk production, but some may harm a nursing baby. Do not take ascorbic acid without telling your doctor if you are breast-feeding a baby.

How should I take ascorbic acid?


Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.


The recommended dietary allowance of ascorbic acid increases with age, and whether you are pregnant or breast-feeding. Follow your doctor's instructions. You may also consult the National Academy of Sciences "Dietary Reference Intake" or the U.S. Department of Agriculture's "Dietary Reference Intake" (formerly "Recommended Daily Allowances" or RDA) listings for more information.


Take the ascorbic acid regular tablet or capsule with a full glass (8 ounces) of water.

The ascorbic acid chewable tablet must be chewed before swallowing. Ascorbic acid gum may be chewed over a long period and then spit out and thrown away.


Remove the disintegrating tablet from the package using dry hands, and place the tablet in your mouth. It will begin to dissolve right away. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves.


Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.


Dissolve the powder form of ascorbic acid in a small amount of water or other liquid. Follow the directions on the package label about what types of liquid you may use. Stir the mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.


Store ascorbic acid at room temperature away from moisture and heat.

What happens if I miss a dose?


Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of ascorbic acid is not likely to cause life-threatening symptoms.


What should I avoid while taking ascorbic acid?


Follow your doctor's instructions about any restrictions on food, beverages, or activity.


Smoking can make ascorbic acid less effective.

Ascorbic acid side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using ascorbic acid and call your doctor at once if you have a serious side effect such as:

  • severe pain in your lower back or side;




  • blood in your urine;




  • pain when you urinate;




  • severe or ongoing diarrhea; or




  • feeling like you might pass out.



Less serious side effects may include:



  • heartburn, stomach cramps;




  • nausea, vomiting, diarrhea;




  • headache, dizziness;




  • flushing (warmth, redness, or tingling under your skin);



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect ascorbic acid?


Ascorbic acid can be harmful to the kidneys, and this effect is increased when ascorbic acid is used together with other medicines that can harm the kidneys. Before taking ascorbic acid, tell your doctor if you are receiving chemotherapy, or using medicines to treat a bowel disorder, medication to prevent organ transplant rejection, antiviral medications, pain or arthritis medicines, or any injected antibiotics.


You may need dose adjustments or special tests when taking any of these medications together with ascorbic acid.


The following drugs can interact with ascorbic acid. Tell your doctor if you are using any of these:



  • aspirin or acetaminophen (Tylenol);




  • fluphenazine (Permitil);




  • indinavir (Crixivan);




  • levodopa (Atamet, Larodopa, Parcopa, Sinemet);




  • nicotine patches (Nicoderm, Habitrol, Commit);




  • antacids that contain aluminum (such as Amphojel, Maalox, Mylanta, Rulox, and others);




  • an antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap); or




  • a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton);




  • birth control pills or hormone replacement therapy, including Premarin, Estratest, Vivelle, Climara, Estring, Estrace, and others; or




  • a blood thinner such as warfarin (Coumadin).



This list is not complete and there may be other drugs that can interact with ascorbic acid. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More Ascorbic Acid Quick Melts resources


  • Ascorbic Acid Quick Melts Side Effects (in more detail)
  • Ascorbic Acid Quick Melts Use in Pregnancy & Breastfeeding
  • Ascorbic Acid Quick Melts Drug Interactions
  • Ascorbic Acid Quick Melts Support Group
  • 0 Reviews for Ascorbic Acid Quick Melts - Add your own review/rating


  • Ascorbic Acid Monograph (AHFS DI)

  • ascorbic acid Advanced Consumer (Micromedex) - Includes Dosage Information

  • Ascorbic Acid MedFacts Consumer Leaflet (Wolters Kluwer)

  • Acerola Natural MedFacts for Consumers (Wolters Kluwer)

  • Acerola Natural MedFacts for Professionals (Wolters Kluwer)

  • Cecon Solution MedFacts Consumer Leaflet (Wolters Kluwer)

  • Cenolate Injection MedFacts Consumer Leaflet (Wolters Kluwer)

  • Cevi-Bid Controlled-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Ascorbic Acid Quick Melts with other medications


  • Dietary Supplementation
  • Scurvy
  • Urinary Acidification


Where can I get more information?


  • Your doctor, pharmacist, or health care provider may have more information about ascorbic acid.

See also: Ascorbic Acid Quick Melts side effects (in more detail)



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Acetaminophen/Dextromethorphan/Pseudoephedrine Drops


Pronunciation: a-seet-a-MIN-oh-fen/dex-troe-meth-OR-fan/sue-doe-eh-FED-rin
Generic Name: Acetaminophen/Dextromethorphan/Pseudoephedrine
Brand Name: Tylenol Infants Plus Cold/Cough


Acetaminophen/Dextromethorphan/Pseudoephedrine Drops are used for:

Relieving pain, congestion, and cough due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.


Acetaminophen/Dextromethorphan/Pseudoephedrine Drops are an analgesic, decongestant, and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, which helps you breathe more easily. The analgesic and cough suppressant work in the brain to decrease pain and reduce the cough reflex.


Do NOT use Acetaminophen/Dextromethorphan/Pseudoephedrine Drops if:


  • you are allergic to any ingredient in Acetaminophen/Dextromethorphan/Pseudoephedrine Drops

  • you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)

  • you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Acetaminophen/Dextromethorphan/Pseudoephedrine Drops:


Some medical conditions may interact with Acetaminophen/Dextromethorphan/Pseudoephedrine Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of glaucoma, an enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, an overactive thyroid, seizures, stroke, or liver problems, or if you consume more than 3 alcohol-containing drinks per day

  • if you have a history of asthma, chronic cough, chronic obstructive pulmonary disease (COPD), or other lung problems (eg, chronic bronchitis, emphysema), or if your cough produces large amounts of mucus

Some MEDICINES MAY INTERACT with Acetaminophen/Dextromethorphan/Pseudoephedrine Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, isoniazid, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects from Acetaminophen/Dextromethorphan/Pseudoephedrine Drops may be increased

  • Anticoagulants (eg, warfarin), digoxin, or droxidopa because the risk of side effects such as bleeding, irregular heartbeat, or heart attack may be increased

  • Bromocriptine because the risk of side effects may be increased by Acetaminophen/Dextromethorphan/Pseudoephedrine Drops

  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Acetaminophen/Dextromethorphan/Pseudoephedrine Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acetaminophen/Dextromethorphan/Pseudoephedrine Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Acetaminophen/Dextromethorphan/Pseudoephedrine Drops:


Use Acetaminophen/Dextromethorphan/Pseudoephedrine Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Acetaminophen/Dextromethorphan/Pseudoephedrine Drops may be taken with or without food.

  • Use the dropper that comes with Acetaminophen/Dextromethorphan/Pseudoephedrine Drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • If you miss a dose of Acetaminophen/Dextromethorphan/Pseudoephedrine Drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acetaminophen/Dextromethorphan/Pseudoephedrine Drops.



Important safety information:


  • Acetaminophen/Dextromethorphan/Pseudoephedrine Drops may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Acetaminophen/Dextromethorphan/Pseudoephedrine Drops. Using Acetaminophen/Dextromethorphan/Pseudoephedrine Drops alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Do not take appetite suppressants while you are taking Acetaminophen/Dextromethorphan/Pseudoephedrine Drops without checking with your doctor.

  • Acetaminophen/Dextromethorphan/Pseudoephedrine Drops contains acetaminophen and pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains acetaminophen or pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.

  • Do NOT exceed the recommended dose or take Acetaminophen/Dextromethorphan/Pseudoephedrine Drops for longer than prescribed without checking with your doctor.

  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.

  • Acetaminophen/Dextromethorphan/Pseudoephedrine Drops may cause liver damage. If you consume 3 or more alcohol-containing drinks every day, ask your doctor if you should take Acetaminophen/Dextromethorphan/Pseudoephedrine Drops or other pain relievers/fever reducers. Alcohol use combined with Acetaminophen/Dextromethorphan/Pseudoephedrine Drops may increase your risk for liver damage.

  • Acetaminophen/Dextromethorphan/Pseudoephedrine Drops may interfere with certain lab test results. Make sure that all of your doctors and lab personnel know that you are taking Acetaminophen/Dextromethorphan/Pseudoephedrine Drops.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Acetaminophen/Dextromethorphan/Pseudoephedrine Drops.

  • Use Acetaminophen/Dextromethorphan/Pseudoephedrine Drops with caution in the ELDERLY because they may be more sensitive to its effects.

  • Caution is advised when using Acetaminophen/Dextromethorphan/Pseudoephedrine Drops in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Acetaminophen/Dextromethorphan/Pseudoephedrine Drops, discuss with your doctor the benefits and risks of using Acetaminophen/Dextromethorphan/Pseudoephedrine Drops during pregnancy. It is unknown if Acetaminophen/Dextromethorphan/Pseudoephedrine Drops are excreted in breast milk. Do not breast-feed while taking Acetaminophen/Dextromethorphan/Pseudoephedrine Drops.


Possible side effects of Acetaminophen/Dextromethorphan/Pseudoephedrine Drops:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; stomach pain; tremor; yellowing of skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Acetaminophen/Dextromethorphan/Pseudoephedrine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; stomach pain; unusually fast, slow, or irregular heartbeat; vomiting; yellowing of skin or eyes.


Proper storage of Acetaminophen/Dextromethorphan/Pseudoephedrine Drops:

Store Acetaminophen/Dextromethorphan/Pseudoephedrine Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acetaminophen/Dextromethorphan/Pseudoephedrine Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about Acetaminophen/Dextromethorphan/Pseudoephedrine Drops, please talk with your doctor, pharmacist, or other health care provider.

  • Acetaminophen/Dextromethorphan/Pseudoephedrine Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Acetaminophen/Dextromethorphan/Pseudoephedrine Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Acetaminophen/Dextromethorphan/Pseudoephedrine resources


  • Acetaminophen/Dextromethorphan/Pseudoephedrine Side Effects (in more detail)
  • Acetaminophen/Dextromethorphan/Pseudoephedrine Use in Pregnancy & Breastfeeding
  • Acetaminophen/Dextromethorphan/Pseudoephedrine Drug Interactions
  • Acetaminophen/Dextromethorphan/Pseudoephedrine Support Group
  • 1 Review for Acetaminophen/Dextromethorphan/Pseudoephedrine - Add your own review/rating


Compare Acetaminophen/Dextromethorphan/Pseudoephedrine with other medications


  • Cold Symptoms


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Potassium Phosphate Powder for Solution


Pronunciation: poe-TASS-ee-um FOS-fate
Generic Name: Potassium Phosphate
Brand Name: Neutra-Phos-K


Potassium Phosphate Powder for Solution is used for:

Preventing kidney stones. It may also be used for other conditions as determined by your doctor.


Potassium Phosphate Powder for Solution is a urinary acidifier. It works by increasing the amount of acid in the urine, which lowers the pH of the urine. This may reduce the growth of some bacteria in the urine and help dissolve calcium kidney stones.


Do NOT use Potassium Phosphate Powder for Solution if:


  • you are allergic to any ingredient in Potassium Phosphate Powder for Solution

  • you have severe adrenal insufficiency (Addison disease), infected kidney stones, struvite stones, severe kidney damage, or high levels of phosphates or potassium in the blood

  • you are taking a potassium-sparing diuretic (eg, triamterene)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Potassium Phosphate Powder for Solution:


Some medical conditions may interact with Potassium Phosphate Powder for Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you are on a sodium- or potassium-restricted diet

  • if you have heart disease or heart failure, kidney problems, myotonia congenita, swelling of the hands and feet, difficulty breathing due to swelling of the lungs, liver problems, severe burns, softening of the bones, high sodium levels in the blood, high blood pressure, an underactive adrenal gland, inflammation of the pancreas, or rickets

  • if you are dehydrated

Some MEDICINES MAY INTERACT with Potassium Phosphate Powder for Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Aldosterone blockers (eg, eplerenone), angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), or potassium-sparing diuretics (eg, triamterene) because high potassium levels, possibly with irregular heartbeat or a heart attack, may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Potassium Phosphate Powder for Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Potassium Phosphate Powder for Solution:


Use Potassium Phosphate Powder for Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Potassium Phosphate Powder for Solution is usually taken after meals and at bedtime. Ask your doctor when you should take Potassium Phosphate Powder for Solution.

  • Packet - Empty contents of 1 packet into one third of a glass of water (about 75 mL/2.5 ounces). Stir the solution vigorously until all particles are dissolved.

  • Bottle - Dissolve entire contents of 1 bottle in 1 gallon of water or other liquid (eg, milk, juice) and take as directed by your doctor. Do not add any additional liquid, but chill the solution if you have trouble drinking it. The solution may be stored for up to 60 days after mixing.

  • Do not take antacids containing aluminum, magnesium, or calcium with Potassium Phosphate Powder for Solution without checking with your doctor or pharmacist.

  • If you miss a dose of Potassium Phosphate Powder for Solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Potassium Phosphate Powder for Solution.



Important safety information:


  • Potassium Phosphate Powder for Solution may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Potassium Phosphate Powder for Solution. Using Potassium Phosphate Powder for Solution alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • While taking Potassium Phosphate Powder for Solution, the possibility of passing old kidney stones is increased.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Potassium Phosphate Powder for Solution, discuss with your doctor the benefits and risks of using Potassium Phosphate Powder for Solution during pregnancy. It is unknown if Potassium Phosphate Powder for Solution is excreted in breast milk. If you are or will be breast-feeding while you are using Potassium Phosphate Powder for Solution, check with your doctor or pharmacist to discuss the risks to your baby.


Possible side effects of Potassium Phosphate Powder for Solution:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Abdominal pain; diarrhea; nausea; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); decreased urination; seizures; shortness of breath; unusual tiredness or weakness.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Potassium Phosphate side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Potassium Phosphate Powder for Solution:

Store Potassium Phosphate Powder for Solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. The solution may be chilled after mixing and stored for up to 60 days. Keep Potassium Phosphate Powder for Solution out of the reach of children and away from pets.


General information:


  • If you have any questions about Potassium Phosphate Powder for Solution, please talk with your doctor, pharmacist, or other health care provider.

  • Potassium Phosphate Powder for Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Potassium Phosphate Powder for Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Potassium Phosphate resources


  • Potassium Phosphate Side Effects (in more detail)
  • Potassium Phosphate Use in Pregnancy & Breastfeeding
  • Potassium Phosphate Drug Interactions
  • Potassium Phosphate Support Group
  • 0 Reviews for Potassium Phosphate - Add your own review/rating


Compare Potassium Phosphate with other medications


  • Constipation
  • Dietary Supplementation
  • Hypophosphatemia


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Wednesday, October 26, 2016

Parnate


Generic Name: tranylcypromine (Oral route)

tran-il-SIP-roe-meen

Oral route(Tablet)

Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults in short-term studies with major depressive disorder (MDD) and other psychiatric disorders. Short term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24, and there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. This risk must be balanced with the clinical need. Monitor patients closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Not approved for use in pediatric patients .



Commonly used brand name(s)

In the U.S.


  • Parnate

Available Dosage Forms:


  • Tablet

Therapeutic Class: Antidepressant


Pharmacologic Class: Monoamine Oxidase Inhibitor, Nonselective


Uses For Parnate


Tranylcypromine is used to treat certain types of depression. It belongs to the group of medicines called monoamine oxidase inhibitors (MAOI). This medicine works by blocking the action of a chemical substance known as monoamine oxidase (MAO) in the nervous system.


Although this medicine is very effective for certain patients, it may also cause some unwanted reactions if taken the wrong way. It is very important to avoid certain foods, beverages, and medicines while you are using tranylcypromine. Your doctor may provide a list as a reminder of which products you should avoid.


This medicine is available only with your doctor's prescription.


Before Using Parnate


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of tranylcypromine in the pediatric population. Safety and efficacy have not been established.


Geriatric


No information is available on the relationship of age to the effects of tranylcypromine in geriatric patients. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving tranylcypromine.


Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Amitriptyline

  • Amoxapine

  • Amphetamine

  • Apraclonidine

  • Atomoxetine

  • Benzphetamine

  • Brimonidine

  • Bupropion

  • Buspirone

  • Carbamazepine

  • Citalopram

  • Clomipramine

  • Clovoxamine

  • Cyclobenzaprine

  • Cyproheptadine

  • Desipramine

  • Desvenlafaxine

  • Dexfenfluramine

  • Dexmethylphenidate

  • Dextroamphetamine

  • Dextromethorphan

  • Diethylpropion

  • Dopamine

  • Dothiepin

  • Doxepin

  • Duloxetine

  • Epinephrine

  • Escitalopram

  • Femoxetine

  • Fenfluramine

  • Fluoxetine

  • Furazolidone

  • Guanadrel

  • Guanethidine

  • Imipramine

  • Isocarboxazid

  • Isometheptene

  • Levodopa

  • Levomethadyl

  • Linezolid

  • Lisdexamfetamine

  • Lofepramine

  • Maprotiline

  • Mazindol

  • Meperidine

  • Mephentermine

  • Methamphetamine

  • Methotrimeprazine

  • Methyldopa

  • Methylene Blue

  • Methylphenidate

  • Milnacipran

  • Mirtazapine

  • Morphine

  • Morphine Sulfate Liposome

  • Nefopam

  • Nortriptyline

  • Opipramol

  • Pargyline

  • Paroxetine

  • Phendimetrazine

  • Phenelzine

  • Phenmetrazine

  • Phentermine

  • Phenylalanine

  • Phenylephrine

  • Phenylpropanolamine

  • Procarbazine

  • Protriptyline

  • Pseudoephedrine

  • Rasagiline

  • Reserpine

  • Rizatriptan

  • Selegiline

  • Sertraline

  • Sibutramine

  • Sumatriptan

  • Tapentadol

  • Tetrabenazine

  • Tranylcypromine

  • Trimipramine

  • Tryptophan

  • Venlafaxine

  • Vilazodone

  • Zolmitriptan

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Albuterol

  • Altretamine

  • Arformoterol

  • Avocado

  • Bambuterol

  • Bitolterol

  • Bitter Orange

  • Broxaterol

  • Clenbuterol

  • Difenoxin

  • Diphenoxylate

  • Disulfiram

  • Droperidol

  • Entacapone

  • Ephedrine

  • Ethchlorvynol

  • Fenoterol

  • Fentanyl

  • Fluvoxamine

  • Formoterol

  • Guarana

  • Hexoprenaline

  • Hydromorphone

  • Indacaterol

  • Isoetharine

  • Kava

  • Levalbuterol

  • Licorice

  • Ma Huang

  • Mate

  • Metaraminol

  • Methoxamine

  • Metoclopramide

  • Nefazodone

  • Oxycodone

  • Pirbuterol

  • Procaterol

  • Reboxetine

  • Rimiterol

  • Ritodrine

  • Salmeterol

  • St John's Wort

  • Sumatriptan

  • Terbutaline

  • Tolcapone

  • Tramadol

  • Tulobuterol

  • Tyrosine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acarbose

  • Acetohexamide

  • Benfluorex

  • Chlorpropamide

  • Ginseng

  • Gliclazide

  • Glimepiride

  • Glipizide

  • Gliquidone

  • Glyburide

  • Guar Gum

  • Insulin

  • Insulin Aspart, Recombinant

  • Insulin Glulisine

  • Insulin Lispro, Recombinant

  • Metformin

  • Miglitol

  • Repaglinide

  • Tolazamide

  • Tolbutamide

  • Troglitazone

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following is not recommended. Your doctor may decide not to treat you with this medication, change some of the other medicines you take, or give you special instructions about the use of food, alcohol, or tobacco.


  • Caffeine

  • Tyramine Containing Food

Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Bipolar disorder (manic-depressive illness) or

  • Headache, history of or

  • Heart or blood vessel disease or

  • Hypertension (high blood pressure) or

  • Liver disease, history of or

  • Pheochromocytoma (an adrenal problem) or

  • Stroke, history of—Should not be used in patients with these conditions.

  • Diabetes or

  • Hyperthyroidism (overactive thyroid or

  • Hypotension (low blood pressure)—Use with caution. May make these conditions worse.

  • Kidney disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.

Proper Use of Parnate


Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.


This medicine should come with a medication guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (tablets):
    • For depression:
      • Adults—At first, 30 milligrams (mg) per day, given in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 60 mg per day.

      • Children—Use is not recommended.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Parnate


It is very important that your doctor check your progress at regular visits to allow for changes in your dose and to check for any unwanted effects.


You will also need to have your blood pressure measured before starting this medicine and while you are using it. If you notice any change to your recommended blood pressure, call your doctor right away. If you have questions about this, talk to your doctor.


When taken with certain foods, drinks, or other medicines, tranylcypromine can cause very dangerous reactions, such as sudden high blood pressure (also called hypertensive crisis). To avoid such reactions, follow these rules of caution:


  • Do not eat foods that have a high tyramine content (most common in foods that are aged or fermented to increase their flavor), such as cheese (especially strong or aged kinds), caviar, sour cream, liver, canned figs, soy sauce, sauerkraut, fava beans, yeasts, and yogurt. Avoid smoked or pickled meat, poultry, or fish, such as sausage, pepperoni, salami, anchovies, or herring. Do not eat dried fruit (such as raisins), bananas, avocados, raspberries, or very ripe fruit.

  • Do not drink alcoholic beverages. This includes Chianti wine, sherry, beer, non-alcohol or low alcohol beer and wine, and liqueurs.

  • Do not eat or drink too much caffeine. Caffeine can be found in coffee, cola, chocolate, tea, and many other foods and drinks. Ask your doctor how much caffeine is safe to use.

Tranylcypromine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you or your caregiver notice any of these adverse effects, tell your doctor right away.


Call your doctor or hospital emergency room right away if you have a severe headache, stiff or sore neck, chest pains, fast heartbeat, sweating, dizziness, or nausea and vomiting while you are taking this medicine. These may be symptoms of a serious side effect called hypertensive crisis.


This medicine may cause blurred vision or make some people drowsy or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are unable to see well or not alert.


This medicine will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.


Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. Getting up slowly may help. When you get up from lying down, sit on the edge of the bed with your feet dangling for 1 or 2 minutes, then stand up slowly. If the problem continues or gets worse, check with your doctor.


Do not stop taking this medicine without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely.


Before having any kind of surgery, dental treatment, or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine or have used it within the past 10 days. Taking tranylcypromine together with medicines that are used during surgery, dental, or emergency treatments may increase the risk of serious side effects.


Your doctor may want you to carry an identification card stating that you are using this medicine.


This medicine may affect blood sugar levels. If you are diabetic, be especially careful in testing for sugar in your blood or urine. If you have any questions about this, check with your doctor.


After you stop using this medicine, you must continue to exercise caution for at least 2 weeks with your foods, drinks, and other medicines, since these items may continue to react with tranylcypromine.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


Parnate Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Incidence not known
  • Absence of or decrease in body movement

  • actions that are out of control

  • agitation

  • anxiety

  • black, tarry stools

  • bleeding gums

  • blood in the urine or stools

  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

  • chest pain

  • chills

  • coma

  • confusion

  • confusion about identity, place, and time

  • cough or hoarseness

  • dark urine

  • decrease in frequency of urination

  • decrease in urine volume

  • depression

  • difficulty in passing urine (dribbling)

  • dizziness

  • dry mouth

  • fast, irregular, pounding, or racing heartbeat or pulse

  • fever

  • fever with or without chills

  • general feeling of tiredness or weakness

  • headache

  • hostility

  • hyperventilation

  • increased need to urinate

  • irregular heartbeats

  • irritability

  • lethargy

  • light-colored stools

  • longer than usual time to ejaculation of semen

  • loss of bladder control

  • lower back or side pain

  • muscle twitching

  • nausea and vomiting

  • nervousness

  • painful or difficult urination

  • pale skin

  • passing urine more often

  • pinpoint red spots on the skin

  • rapid weight gain

  • restlessness

  • seizures

  • shakiness and unsteady walk

  • shortness of breath

  • sore throat

  • sores, ulcers, or white spots on the lips or in the mouth

  • stupor

  • sudden jerky movements of the body

  • swelling

  • swelling of the face, ankles, or hands

  • swollen glands

  • talking, feeling, and acting with excitement

  • trouble with sleeping

  • troubled breathing with exertion

  • unsteadiness, trembling, or other problems with muscle control or coordination

  • unusual bleeding or bruising

  • unusual tiredness or weakness

  • upper right abdominal pain

  • yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Incidence not known
  • Abdominal or stomach pain

  • blurred vision

  • constipation

  • continuing ringing or buzzing or other unexplained noise in the ears

  • decreased interest in sexual intercourse

  • diarrhea

  • drowsiness

  • dry mouth

  • hair loss or thinning of the hair

  • hearing loss

  • hives or welts

  • inability to have or keep an erection

  • itching

  • loss in sexual ability, desire, drive, or performance

  • loss of appetite

  • memory loss

  • muscle spasm

  • redness of the skin

  • skin rash

  • sleeplessness

  • unable to sleep

  • weakness

  • weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Parnate side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Parnate resources


  • Parnate Side Effects (in more detail)
  • Parnate Dosage
  • Parnate Use in Pregnancy & Breastfeeding
  • Drug Images
  • Parnate Drug Interactions
  • Parnate Support Group
  • 6 Reviews for Parnate - Add your own review/rating


  • Parnate Prescribing Information (FDA)

  • Parnate MedFacts Consumer Leaflet (Wolters Kluwer)

  • Parnate Concise Consumer Information (Cerner Multum)

  • Parnate Monograph (AHFS DI)

  • Tranylcypromine Prescribing Information (FDA)



Compare Parnate with other medications


  • Depression


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Labels:

Ampicillin Suspension



Pronunciation: AM-pi-SIL-in
Generic Name: Ampicillin
Brand Name: Generic only. No brands available.


Ampicillin Suspension is used for:

Treating infections caused by certain bacteria.


Ampicillin Suspension is a penicillin antibiotic. It works by blocking the bacteria's cell wall growth, which kills the bacteria.


Do NOT use Ampicillin Suspension if:


  • you are allergic to any ingredient in Ampicillin Suspension or to any other penicillin antibiotic (eg, amoxicillin)

  • you are taking a tetracycline antibiotic (eg, doxycycline)

  • you have mononucleosis ("mono")

  • you have recently received or will be receiving live oral typhoid vaccine

Contact your doctor or health care provider right away if any of these apply to you.



Before using Ampicillin Suspension:


Some medical conditions may interact with Ampicillin Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to a cephalosporin (eg, cephalexin) or other beta-lactam antibiotic (eg, imipenem)

  • if you have kidney problems

Some MEDICINES MAY INTERACT with Ampicillin Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Allopurinol because the risk of skin rash may be increased

  • Heparin because the risk of bleeding may be increased

  • Probenecid because it may increase the risk of Ampicillin Suspension's side effects

  • Tetracyclines (eg, doxycycline) because they may decrease Ampicillin Suspension's effectiveness

  • Methotrexate because the risk of its side effects may be increased by Ampicillin Suspension

  • Anticoagulants (eg, warfarin) because their effectiveness may be decreased or the risk of their side effects may be increased by Ampicillin Suspension

  • Aminoglycosides (eg, gentamicin), oral contraceptives (eg, ethinyl estradiol/norethindrone), or live oral typhoid vaccine because their effectiveness may be decreased by Ampicillin Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ampicillin Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Ampicillin Suspension:


Use Ampicillin Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Ampicillin Suspension by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

  • Shake well before each use.

  • Take Ampicillin Suspension with a full glass of water (8 oz/240 mL).

  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • To clear up your infection completely, take Ampicillin Suspension for the full course of treatment. Keep using it even if you feel better in a few days.

  • If you miss a dose of Ampicillin Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Ampicillin Suspension.



Important safety information:


  • Ampicillin Suspension only works against bacteria; it does not treat viral infections (eg, the common cold).

  • Be sure to use Ampicillin Suspension for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

  • Long-term or repeated use of Ampicillin Suspension may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

  • If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions.

  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Ampicillin Suspension. To prevent pregnancy, use an extra form of birth control (eg, condoms).

  • Ampicillin Suspension may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Ampicillin Suspension.

  • Diabetes patients - Ampicillin Suspension may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

  • Use Ampicillin Suspension with extreme caution in CHILDREN younger than 10 years old who have diarrhea or an infection of the stomach or bowel.

  • Caution is advised when using Ampicillin Suspension in NEWBORNS and INFANTS; they may be more sensitive to its effects

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ampicillin Suspension while you are pregnant. Ampicillin Suspension is found in breast milk. Do not breast-feed while using Ampicillin Suspension.


Possible side effects of Ampicillin Suspension:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Mild diarrhea; nausea; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; fever, chills, or sore throat; seizures; severe diarrhea; severe nausea or vomiting; stomach pain or cramps; unusual bruising or bleeding; unusual tiredness or weakness; vaginal irritation or discharge; vein inflammation or tenderness; white patches in mouth.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Ampicillin side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include agitation; coma; confusion; hallucinations; tremors.


Proper storage of Ampicillin Suspension:

Store Ampicillin Suspension at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), or in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). If you store Ampicillin Suspension at room temperature, throw away any unused medicine after 7 days. If you store Ampicillin Suspension in the refrigerator, throw away any unused medicine after 14 days. Store in a tightly closed container away from heat, moisture, and light. Do not store in the bathroom. Keep Ampicillin Suspension out of the reach of children and away from pets.


General information:


  • If you have any questions about Ampicillin Suspension, please talk with your doctor, pharmacist, or other health care provider.

  • Ampicillin Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Ampicillin Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Ampicillin resources


  • Ampicillin Side Effects (in more detail)
  • Ampicillin Use in Pregnancy & Breastfeeding
  • Drug Images
  • Ampicillin Drug Interactions
  • Ampicillin Support Group
  • 3 Reviews for Ampicillin - Add your own review/rating


Compare Ampicillin with other medications


  • Bacterial Endocarditis Prevention
  • Bronchitis
  • Endocarditis
  • Gastroenteritis
  • Intraabdominal Infection
  • Kidney Infections
  • Leptospirosis
  • Meningitis
  • Otitis Media
  • Peritonitis
  • Pharyngitis
  • Pneumonia
  • Prevention of Perinatal Group B Streptococcal Disease
  • Septicemia
  • Shigellosis
  • Sinusitis
  • Skin Infection
  • Surgical Prophylaxis
  • Typhoid Fever
  • Upper Respiratory Tract Infection
  • Urinary Tract Infection


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Prialt


Generic Name: Ziconotide
Class: Analgesics and Antipyretics, Miscellaneous
VA Class: CN103
Chemical Name: ω-Conotoxin M VIIA
Molecular Formula: C102H172N36O32S7
CAS Number: 107452-89-1



  • Risk of severe psychiatric symptoms and neurological impairment.1 Do not use in patients with a history of psychosis.1 (See Nervous System Effects under Cautions.)




  • Monitor for cognitive impairment, hallucinations, and changes in mood or consciousness.1




  • Ziconotide therapy can be interrupted or discontinued abruptly without withdrawal effects.1




Introduction

Potent nonopiate analgesic; synthetic conopeptide isolated from venom of the marine snail Conus magus.1 2 3 4 5


Uses for Prialt


Severe Chronic Pain


Used intrathecally for relief of severe chronic pain in patients who are intolerant of or do not obtain adequate pain relief from other therapies (e.g., systemic analgesics, adjunctive therapies, intrathecal morphine therapy) when intrathecal therapy is warranted.1 2 3 5


Prialt Dosage and Administration


Administration


Administer intrathecally by or under the supervision of a qualified clinician familiar with the drug, the techniques of intrathecal administration, and the device being used.1


Do not administer IV.1


Intrathecal Administration


Administer using a programmable implanted variable-rate microinfusion device (i.e., Medtronic SynchroMed EL or SynchroMed II) or an external microinfusion device and catheter (i.e., CADD-Micro ambulatory infusion pump).1


Consult manufacturer's labeling for specialized administration techniques.1


Consult the manual provided by the manufacturer of the infusion device for specific instructions and precautions for performing a reservoir rinse, initial filling, refilling the reservoir or replacing the drug cartridge, and programming.1


Dilution

Select an appropriate vial strength and final concentration of the drug according to the manufacturer's instructions.1


The commercially available preparation containing ziconotide 25 mcg/mL may be used undiluted.1


The commercially available preparation containing ziconotide 100 mcg/mL may be used undiluted or diluted with preservative-free 0.9% sodium chloride injection prior to placement in the pump.1


Sodium chloride solutions containing preservatives are not appropriate for intrathecal administration and should not be used to dilute ziconotide.1


Initiate infusion of diluted solutions within 24 hours of preparation.1


Dosage


Adults


Severe Chronic Pain

Intrathecal

Initiate using slow dose titration schedule to minimize risk for serious adverse effects.1 (See Common Adverse Effects under Cautions.)


Initially, no more than 2.4 mcg per 24 hours (0.1 mcg/hour).1 Increase dosage based on patient response 2 or 3 times weekly in increments of up to 2.4 mcg per 24 hours (0.1 mcg/hour), up to maximum recommended dosage of 19.2 mcg per 24 hours (0.8 mcg/hour) by day 21.1


Average dosage at day 21 in clinical studies that used the slow titration schedule was 6.9 mcg per 24 hours (0.29 mcg/hour).1


Alternatively, a faster titration schedule can be used if need for urgent analgesia outweighs risk.1 In the fast schedule, dosage is increased daily up to a maximum dosage of 57.6 mcg per 24 hours (2.4 mcg/hr) after 5–6 days.1


Therapy can be interrupted or discontinued abruptly without withdrawal effects.1


Special Populations


Hepatic Impairment


No dosage recommendations.1


Renal Impairment


No dosage recommendations.1


Geriatric Patients


Select dosage with caution, starting at the lower end of the dosage range.1 (See Geriatric Use under Cautions.)


Cautions for Prialt


Contraindications



  • Concomitant treatments or medical condition that would make intrathecal administration hazardous (e.g., infection at the microinfusion site, uncontrolled bleeding diathesis, spinal canal obstruction that impairs CSF circulation).1




  • History of psychosis.1




  • Known hypersensitivity to ziconotide or any ingredient in the formulation.1



Warnings/Precautions


Warnings


Nervous System Effects

Acute psychiatric disturbances (e.g., hallucinations, paranoid reactions, hostility, delirium, psychosis, manic reactions) reported.1 Risk may be increased in patients with preexisting psychiatric disorders.1 May cause or worsen depression, resulting in risk of suicide in certain patients.1 If psychiatric disturbances occur, discontinue ziconotide and manage psychosis.1 Careful evaluation needed before reinitiating ziconotide.1


Cognitive impairment (e.g., confusion, memory impairment, speech disorder, aphasia, abnormal thinking, amnesia) reported; generally develops gradually over several weeks and usually is reversible following discontinuance of the drug.1 If cognitive impairment occurs, discontinue or temporarily interrupt ziconotide.1 Consider other causes that may contribute to cognitive impairment.1


Reduced levels of consciousness (e.g., patient is unresponsive or stuporous) reported.1 Increased risk for this adverse effect observed in patients receiving concomitant anticonvulsants, antipsychotics, sedatives, or diuretics.1 If reduced levels of consciousness occurs, discontinue ziconotide until the event resolves; evaluate for other etiologies.1 Discontinue concomitant CNS depressants as clinically appropriate.1


Opiate Withdrawal

Does not prevent or treat the symptoms of opiate withdrawal.1 Avoid withdrawal symptoms in patients discontinuing intrathecal opiate therapy by gradually tapering infusion rate over a few weeks and replacing with equivalent doses of oral opiates.1


Major Toxicities


Meningitis

Meningitis reported rarely; incidence higher in patients with external devices than in those with internal devices.1 May occur secondary to inadvertent contamination of device or from CSF seeding.1


Monitor for signs and symptoms of meningitis (e.g., fever, headache, stiff neck, altered mental status, nausea or vomiting, seizures).1 If meningitis is suspected or confirmed, initiate appropriate measures.1


Prepare doses and fill the drug reservoir under aseptic conditions.1


General Precautions


Serum CK

Possible elevations in CK.1 More likely to occur in men, those receiving antidepressants or anticonvulsants, or those who had received intrathecal morphine.1 Monitor CK concentrations periodically.1 Evaluate patient if neuromuscular symptoms develop.1 If symptoms persist and CK concentrations remain increased or continue to rise, consider dose reduction or drug discontinuation.1


Specific Populations


Pregnancy

Category C.1


Lactation

Not known if ziconotide is distributed into milk.1


Discontinue nursing or the drug.1


Pediatric Use

Safety and efficacy not established in patients <18 years of age.1 6


Geriatric Use

Increased incidence of confusion in patients ≥65 years of age.1 No substantial difference in efficacy relative to younger adults.1


Select dose with caution, starting at the lower end of the dosage range, because of age-related decreases in hepatic, renal, and/or cardiac function and potential for concomitant disease and drug therapy.1


Common Adverse Effects


Dizziness, nausea, confusion, headache, somnolence, nystagmus, asthenia, pain.1


Serious adverse events and drug discontinuance due to adverse effects occur less frequently when the dosage is increased slowly over 21 days than when a faster dose titration schedule is used.1


Interactions for Prialt


Drugs Affecting or Metabolized by Hepatic Microsomal Enzymes


Pharmacokinetic interaction unlikely.1


Protein-bound Drugs


Pharmacokinetic interaction unlikely.1


Specific Drugs





















Drug



Interaction



Comments



Anticonvulsants



Increased risk of elevated serum CK concentrations1



Antidepressants



Increased risk of elevated serum CK concentrations1



CNS depressants



Increased risk of dizziness, confusion, reduced consciousness1



Used concomitantly with anticonvulsants, antidepressants, antipsychotics, anxiolytics, and sedatives in studies1


Dosage adjustment or discontinuance of ziconotide or concomitant CNS depressant may be needed1



Diuretics



Increased risk of reduced consciousness1



Opiates



Previous intrathecal morphine sulfate: Increased risk of elevated serum CK concentrations1


Prialt Pharmacokinetics


Absorption


Bioavailability


Intrathecal administration results in little systemic exposure.1


Distribution


Extent


Mean CSF volume of distribution approximates total CSF volume (140 mL).1


Plasma Protein Binding


50%.1


Elimination


Metabolism


Cleaved by various ubiquitous peptidases/proteases present in most organs (e.g., kidney, liver, lung, muscle).1 Minimal hydrolytic activity shown in vitro in CSF and blood.1


Half-life


CSF: 4.6 hours.1


Stability


Storage


Parenteral


Injection

2–8°C; refrigerate during transit.1


Once diluted with preservative-free 0.9% sodium chloride injection, may be stored at 2–8°C for 24 hours.1


Protect from light1


ActionsActions



  • Produces potent antinociceptive effects by selectively binding to N-type voltage-sensitive calcium channels on primary nociceptive afferent nerves in superficial layers of the spinal cord, thus blocking neurotransmission from primary nociceptive afferents.1 2




  • Does not bind to opiate receptors.1 Pharmacologic effects of ziconotide not blocked by opiate antagonists.1 Does not potentiate opiate-induced respiratory depression.1



Advice to Patients



  • Risk of somnolence; avoid driving, operating machinery, or performing hazardous tasks until effects on individual are known.1




  • Importance of informing clinician if new or worsening muscle pain, soreness, weakness, or brown urine develops.1




  • Importance of promptly reporting a change in mental status (e.g., lethargy, confusion, disorientation, decreased alertness), mood or perception (e.g., hallucinations, unusual tactile sensations in the mouth), and symptoms of depression or suicidal ideation.1




  • Importance of promptly informing clinician if symptoms of meningitis (i.e., nausea, vomiting, seizures, fever, headache, stiff neck) occur.1




  • For patients receiving ziconotide via an external microinfusion device and catheter, importance of proper handling of the device and proper care of the skin at the catheter exit site.1




  • Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed.1




  • Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as concomitant illnesses.1 Potential for additive CNS effects if used concomitantly with other CNS depressants.1




  • Importance of informing patients of other important precautionary information.1 (See Cautions.)



Preparations


Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.


















Ziconotide

Routes



Dosage Forms



Strengths



Brand Names



Manufacturer



Parenteral



Injection, for intrathecal administration via compatible microinfusion device only



25 mcg/mL



Prialt



Elan Pharmaceuticals



100 mcg/mL



Prialt



Elan Pharmaceuticals



Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.


The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions June 2006. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.




References



1. Elan Pharmaceuticals. Prialt (ziconotide) intrathecal infusion prescribing information. San Diego, CA; 2005 Feb.



2. Staats PS, Yearwood T, Charapata SG et al. Intrathecal ziconotide in the treatment of refractory pain in patients with cancer or AIDS: a randomized controlled trial. JAMA. 2004; 291:63-70. [IDIS 509585] [PubMed 14709577]



3. Wermeling D, Drass M, Ellis D et al. Pharmacokinetics and pharmacodynamics of intrathecal ziconotide in chronic pain patients. J Clin Pharmacol. 2003; 43:624-36. [IDIS 500357] [PubMed 12817525]



4. Atanassoff PG, Hartmannsgruber MW, Thrasher J et al. Ziconotide, a new N-type channel blocker, administered intrathecally for acute postoperative pain. Reg Anesth Pain Med. 2000; 25:274-8. [IDIS 532012] [PubMed 10834782]



5. Doggrell SA. Intrathecal ziconotide for refractory pain. Expert Opin Invest Drugs. 2004; 13:875-7.



6. Elan Pharmaceuticals, San Diego, CA: Personal communication.



More Prialt resources


  • Prialt Side Effects (in more detail)
  • Prialt Use in Pregnancy & Breastfeeding
  • Prialt Drug Interactions
  • Prialt Support Group
  • 0 Reviews for Prialt - Add your own review/rating


  • Prialt Prescribing Information (FDA)

  • Prialt Consumer Overview

  • Prialt Advanced Consumer (Micromedex) - Includes Dosage Information

  • Prialt MedFacts Consumer Leaflet (Wolters Kluwer)

  • Ziconotide Professional Patient Advice (Wolters Kluwer)



Compare Prialt with other medications


  • Pain


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Aztreonam inhalation


Generic Name: aztreonam (inhalation) (AZ tree oh nam)

Brand Names: Cayston


What is aztreonam?

Aztreonam is an antibiotic that fights severe or life-threatening infection caused by bacteria.


Aztreonam inhalation is used to improve breathing symptoms in people who have cystic fibrosis and a certain bacteria in their lungs. This medication is for use in adults and children who are at least 7 years old.


Aztreonam may also be used for purposes not listed in this medication guide.


What is the most important information I should know about aztreonam?


You should not use this medication if you are allergic to aztreonam.

Before using aztreonam, tell your doctor if you are allergic to any type of antibiotic, especially a cephalosporin (Ceftin, Cefzil, Keflex, Omnicef, and others), a penicillin (Amoxil, Augmentin, Bactocill, Bicillin C-R, Dycill, Dynapen, Omnipen, Principen, PC Pen VK, Pen-V, Pfizerpen, and others), or similar antibiotics such as Invanz, Primaxin, or Marum.


Use aztreonam for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Aztreonam will not treat a viral infection such as the common cold or flu.


Aztreonam inhalation should be used only with an Altera brand nebulizer. Do not use any other type of nebulizer or inhaler device with this medication. Do not mix other medicines with aztreonam in the nebulizer. If you use other inhaled medications, you may need to use them in a certain order while using aztreonam inhalation. Ask your doctor for specific instructions about when to use your other medications in relation to your aztreonam inhalation doses.

What should I discuss with my health care provider before using aztreonam?


You should not use this medication if you are allergic to aztreonam.

Before using aztreonam, tell your doctor if you are allergic to any type of antibiotic, especially:



  • cephalosporins such as cefdinir (Omnicef), cefprozil (Cefzil), cefuroxime (Ceftin), cephalexin (Keflex), and others;




  • penicillins such as amoxicillin (Amoxil, Augmentin), ampicillin (Omnipen, Principen), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), or penicillin (Bicillin C-R, PC Pen VK, Pen-V, Pfizerpen), and others; or




  • similar antibiotics such as ertapenem (Invanz), imipenem (Primaxin), or meropenem (Merrem).




If you have kidney disease, you may need an aztreonam dose adjustment or special tests. FDA pregnancy category B. Aztreonam is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Aztreonam can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use aztreonam?


Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.


Aztreonam inhalation should be used only with an Altera brand nebulizer. Do not use any other type of nebulizer or inhaler device with this medication. Do not mix other medicines with aztreonam in the nebulizer.

Astreonam inhalation is a powder medicine that must be mixed with a liquid (diluent) just before using it. Be sure you understand how to properly mix the medication before pouring it into the nebulizer.


Prepare aztreonam in the nebulizer only when you are ready to give yourself a dose. Swirl the mixture gently until the powder has dissolved, then pour the mixture into the handset of the nebulizer. Use the medicine right away after placing it in the nebulizer. Do not save it for later use.


Do not use the medication if it looks cloudy or has particles in it. Call your doctor for a new prescription.

Each vial (bottle) of aztreonam and each ampule of diluent are for one use only. Throw away the empty bottle and ampule after mixing one dose, even if there is diluent left in the ampule.


Aztreonam inhalation is usually given 3 times daily for 28 days. Follow your doctor's dosing instructions very carefully. Your doses should be spaced at least 4 hours apart.


You may need to use a bronchodilator medication before each dose of aztreonam inhalation. Follow your doctor's instructions about the type of bronchodilator to use and when to use it.


Use aztreonam for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Aztreonam will not treat a viral infection such as the common cold or flu.


Do not give this medication to another person, even if they have the same symptoms you have. Store the powder and diluent in the refrigerator, do not freeze. After taking the powder and diluent out of the refrigerator, you may store them at room temperature away from moisture, heat, and light. This medicine must be used within 28 days if you keep it at room temperature.

What happens if I miss a dose?


Use the missed dose as soon as you remember. Then wait at least 4 hours before using your next dose. Even if you miss a dose, you should still try to get all of your scheduled doses for the day, as long as they are spaced at least 4 hours apart. Do not use two doses at one time or use extra medicine to make up a missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using aztreonam?


Follow your doctor's instructions about any restrictions on food, beverages, or activity.


Aztreonam side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • bronchospasm (wheezing, chest tightness, trouble breathing) right after using the medicine; or




  • any new or worsening symptoms.



Less serious side effects may include:



  • mild stomach discomfort, vomiting;




  • cough, sore throat;




  • stuffy nose; or




  • low fever.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


Aztreonam Dosing Information


Usual Adult Dose for Bacteremia:

2 g IV every 6 to 8 hours

Therapy should be continued for approximately 10 to 14 days, depending on the nature and severity of the infection.

Usual Adult Dose for Bacterial Infection:

Moderately severe infections: 1 to 2 g IV or IM every 8 to 12 hours
Severe infections: 2 g IV every 6 to 8 hours (maximum, 8 g/day)

Usual Adult Dose for Cystic Fibrosis:

Inhalation:
Initial dose: 75 mg via nebulizer over approximately 2 to 3 minutes 3 times a day for 28 days; doses should be at least 4 hours apart

Maintenance dose: Administer in alternating cycles of 28 days on and 28 days off.

For patients on multiple inhaled therapies, the following order of administration is recommended: bronchodilator, mucolytics, and lastly, aztreonam for inhalation.

Usual Adult Dose for Febrile Neutropenia:

2 g IV every 6 to 8 hours

Therapy should be continued until the absolute neutrophil count is greater than 500/mm3 and no infection is found or until an adequate clinical response is achieved if a susceptible infection is found and the patient has been afebrile for at least 24 hours. Therapy for neutropenic patients is often required for up to 3 weeks.

Usual Adult Dose for Intraabdominal Infection:

1 to 2 g IV every 8 or 12 hours

For severe or life-threatening infections, a dose of 2 g IV every 6 to 8 hours is recommended. Therapy should be continued for approximately 10 to 14 days, depending on the nature and severity of the infection.

Usual Adult Dose for Peritonitis:

1 to 2 g IV every 8 or 12 hours

For severe or life-threatening infections, a dose of 2 g IV every 6 to 8 hours is recommended. Therapy should be continued for approximately 10 to 14 days, depending on the nature and severity of the infection.

Usual Adult Dose for Osteomyelitis:

1 to 2 g IV every 8 or 12 hours

For severe or life-threatening infections, a dose of 2 g IV every 6 to 8 hours is recommended. Therapy should be continued for approximately 4 to 6 weeks, depending on the nature and severity of the infection. Chronic osteomyelitis may require an additional 2 months of oral antibiotics.

Usual Adult Dose for Pelvic Inflammatory Disease:

1 to 2 g IV every 8 or 12 hours

For severe or life-threatening infections, a dose of 2 g IV every 6 to 8 hours is recommended. Therapy should be continued until this patient is afebrile and pain-free for 24 to 36 hours.

Usual Adult Dose for Pneumonia:

1 to 2 g IV every 8 or 12 hours

For severe or life-threatening infections, a dose of 2 g IV every 6 to 8 hours is recommended. Therapy should be continued for approximately 21 days, depending on the nature and severity of the infection.

Usual Adult Dose for Pyelonephritis:

1 to 2 g IV every 8 or 12 hours

For severe or life-threatening infections, a dose of 2 g IV every 6 to 8 hours is recommended. Therapy should be continued for approximately 14 days, depending on the nature and severity of the infection.

Usual Adult Dose for Skin or Soft Tissue Infection:

1 to 2 g IV every 8 or 12 hours

For severe or life-threatening infections, a dose of 2 g IV every 6 to 8 hours is recommended. Therapy should be continued for approximately 7 days or until 3 days after acute inflammation disappears. For more severe infections, such as diabetic soft tissue infections, 14 to 21 days of therapy may be required.

Usual Adult Dose for Urinary Tract Infection:

500 mg to 1 g IV or IM every 8 to 12 hours

Usual Pediatric Dose for Intraabdominal Infection:

7 days or less, 2000 g or less: 30 mg/kg IV every 12 hours
7 days or less, 2001 g or more: 30 mg/kg IV every 8 hours

8 to 30 days, 1199 g or less: 30 mg/kg IV every 12 hours
8 to 30 days, 1200 to 2000 g: 30 mg/kg IV every 8 hours
8 to 30 days, 2001 g or more: 30 mg/kg IV every 6 hours

1 month to 18 years: 30 mg/kg IV every 6 to 8 hours, up to a maximum of 2 g/dose or 8 g/day

Usual Pediatric Dose for Pneumonia:

7 days or less, 2000 g or less: 30 mg/kg IV every 12 hours
7 days or less, 2001 g or more: 30 mg/kg IV every 8 hours

8 to 30 days, 1199 g or less: 30 mg/kg IV every 12 hours
8 to 30 days, 1200 to 2000 g: 30 mg/kg IV every 8 hours
8 to 30 days, 2001 g or more: 30 mg/kg IV every 6 hours

1 month to 18 years: 30 mg/kg IV every 6 to 8 hours, up to a maximum of 2 g/dose or 8 g/day

Usual Pediatric Dose for Bacterial Infection:

7 days or less, 2000 g or less: 30 mg/kg IV every 12 hours
7 days or less, 2001 g or more: 30 mg/kg IV every 8 hours

8 to 30 days, 1199 g or less: 30 mg/kg IV every 12 hours
8 to 30 days, 1200 to 2000 g: 30 mg/kg IV every 8 hours
8 to 30 days, 2001 g or more: 30 mg/kg IV every 6 hours

1 month to 18 years: 30 mg/kg IV every 6 to 8 hours, up to a maximum of 2 g/dose or 8 g/day

Usual Pediatric Dose for Urinary Tract Infection:

7 days or less, 2000 g or less: 30 mg/kg IV every 12 hours
7 days or less, 2001 g or more: 30 mg/kg IV every 8 hours

8 to 30 days, 1199 g or less: 30 mg/kg IV every 12 hours
8 to 30 days, 1200 to 2000 g: 30 mg/kg IV every 8 hours
8 to 30 days, 2001 g or more: 30 mg/kg IV every 6 hours

1 month to 18 years: 30 mg/kg IV every 6 to 8 hours, up to a maximum of 2 g/dose or 8 g/day

Usual Pediatric Dose for Skin and Structure Infection:

7 days or less, 2000 g or less: 30 mg/kg IV every 12 hours
7 days or less, 2001 g or more: 30 mg/kg IV every 8 hours

8 to 30 days, 1199 g or less: 30 mg/kg IV every 12 hours
8 to 30 days, 1200 to 2000 g: 30 mg/kg IV every 8 hours
8 to 30 days, 2001 g or more: 30 mg/kg IV every 6 hours

1 month to 18 years: 30 mg/kg IV every 6 to 8 hours, up to a maximum of 2 g/dose or 8 g/day

Usual Pediatric Dose for Cystic Fibrosis:

Inhalation:
7 years or older:
Initial dose: 75 mg via nebulizer over approximately 2 to 3 minutes 3 times a day for 28 days; doses should be at least 4 hours apart

Maintenance dose: Administer in alternating cycles of 28 days on and 28 days off.

For patients on multiple inhaled therapies, the following order of administration is recommended: bronchodilator, mucolytics, and lastly, aztreonam for inhalation.


What other drugs will affect aztreonam?


If you use other inhaled medications, you may need to use them in a certain order while using aztreonam inhalation. Ask your doctor for specific instructions about when to use your other medications in relation to your aztreonam inhalation doses.

There may be other drugs that can interact with aztreonam. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More aztreonam resources


  • Aztreonam Side Effects (in more detail)
  • Aztreonam Use in Pregnancy & Breastfeeding
  • Aztreonam Drug Interactions
  • Aztreonam Support Group
  • 0 Reviews for Aztreonam - Add your own review/rating


Compare aztreonam with other medications


  • Bacteremia
  • Bacterial Infection
  • Bone infection
  • Cystic Fibrosis
  • Febrile Neutropenia
  • Intraabdominal Infection
  • Kidney Infections
  • Pelvic Inflammatory Disease
  • Peritonitis
  • Pneumonia
  • Pneumonia with Cystic Fibrosis
  • Skin and Structure Infection
  • Skin Infection
  • Urinary Tract Infection


Where can I get more information?


  • Your doctor or pharmacist can provide more information about aztreonam inhalation.

See also: aztreonam side effects (in more detail)



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